Alzheimer's Disease

  1. The pathway concerning AD
  2. The cortical atrophy leads to compensatory dilation of the cerebral ventricles - "hydrocephalus ex vacuo"
  3. The brain with more pronounced atrophy with Alzheimer's disease
  4. Alzheimer's disease leads to cerebral atrophy, the external surface of the brain with widened sulci and narrowed gyri, mostly over the frontal and parietal regions
  5. Alzheimer's disease, neurofibrillary tangle. The neurons demonstrate intracytoplasmic proliferation of twisted filaments producing the visible "neurofibrillary tangle" under the microscope. These are commonly found in the pyramidal cells of the Hippocampus and the cerebral cortex. H and E stain, microscopic
  6. Alzheimer's disease, neurofibrillary tangle. The tangles are best demonstrated with Bielschowsky silver stain as shown here, microscopic
  7. Transection of the AD's Brain